Fibrin associates formed in the early stages of blood clotting

 

On the earliest stages of thrombus formation thin fibers called protofibrils are formed. They further interact with each other to form larger macroscopic fibers. These early stages of coagulation can be observed in microscopy in diluted solutions of proteins only. Under this conditions along with protofibrils thinner single-stranded associates are formed on a completely different molecular mechanism.

(The image is obtained on Nanoscope III, Digital Instruments, USA)

© Protopopova Anna. Physical department of MSU, Russia

 

 

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