New approaches for biologically safe production of nanoparticles using plants

 

Collaborative research between ATC and The James Hutton Institute

 

Participants Results Publications ATC

 

Participants

Igor V. Yaminsky

 

Occupation in ATC: Director.

Other affiliations: Lomonosov Moscow State University, Professor.

Field of scientific interests: Experimental Nanotechnology, Analytical Bionanoscopy, Surface Science, Scanning Probe Microscopy, Biophysics, Biosensors and Chemical Sensors.

 

 

Selected publications:

1.    Dubrovin, EV., Koroleva, ON., Khodak, YA., Kuzmina, NV., Yaminsky, IV. & Drutsa, VL. AFM study of Escherichia coli RNA polymerase σ70 subunit aggregation. (2012). Nanomedicine: Nanotechnology, Biology and Medicine, 8, 54-62.

2.    Zavyalova, E., Protopopova, AD., Yaminsky, IV., Kopylov, AM. (2012). Kinetic characterization of inhibition of human thrombin with DNA aptamers by turbidimetric assay. Analytical Biochemistry, 412, 234-239.

3.    Efremov, YM., Bagrov, DV., Dubrovin, EV., Shaitan, KV. & Yaminsky, IV. (2011). Atomic Force Microscopy of Animal Cells: Advances and Prospects. Biophysics, 56, 257-267.

4.    Zavyalova, EG., Protopopova, AD., Kopylov, AM., Yaminsky, IV. (2011). Investigation of early stages of fibrin association. Langmuir, 27, 4922 4927.

5.    Sinitsyna, OV., Meshkov, GB. & Yaminsky, IV. (2010). A novel tool for the local anodic oxidation of graphite. Proc. IMechE, Part N: J. Nanoengineering and Nanosystems, 224(N3-4), 133-138.

6.    Makarov, VV., Rybakova, EN., Efimov, AV., Dobrov, EN., Serebryakova, MV., Solovyev, AG., Yaminsky, IV., Taliansky, ME., Morozov, SY. & Kalinina, NO. (2009). Domain organization of the N-terminal portion of hordeivirus movement protein TGBp1. J. Gen. Virol, 90, 3022-3032.

7.    Dubrovin, EV., Voloshin, AG., Ignatyuk, TE., Abramchuk, SS., Yaminsky, IV. & Ignatov, SG. (2008). Atomic force microscopy investigation of phage infection of bacteria. Langmuir, 24, 13068-13074.

8.    Dubrovin, EV., Drygin, YF., Novikov, VK. & Yaminsky, IV. (2007). Atomic force microscopy as a tool of inspection of viral infection. Nanomedicine: Nanotechnology, Biology and Medicine, 3, 128-1311.

 

alinina Natalia legovna

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Occupation in ATC: scientific researcher.

Other affiliations: Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology, Senior Scientific Officer.

Field of scientific interests: plant viruses, biochemical and physico-chemical properties of viral and cellular proteins, analysis of RNA-protein and protein-protein interactions, structural characteristics of virus ribonucleoprotein particles.

 

 

Selected publications:

1.      Taliansky M., Roberts I.M., Kalinina N., Ryabov E.V., Raj S.R., Robinson D.J. and Oparka K.J. An umbraviral protein, involved in long-distance RNA movement, binds viral RNA and forms unique, protective ribonucleoprotein complexes. 2003. Journal of Virology, 77, 3031-3040.

2.      Kalinina N.O. Analysis of biomolecular interactions between plant-virus-encoded and host proteins, and viral particles and proteins by surface plasmon resonance. 2003. Microbiology Today, 30, 136-137.

3.      Andreev I.A, Kim S-H., Kalinina N.O., Rakitina D.V., Fitzgerald A.G., Palukaitis P., Taliansky M.E. Molecular interactions between a plant virus movement protein and RNA: Force spectroscopy investigation. 2004. Journal Molecular Biology, 339, 1041-1047.

4.      Canetta E., Kim S.H., Kalinina N.O., Shaw J., Adya A.K., Gillespie T., Brown J.W., Taliansky M. A plant virus movement protein forms ringlike complexes with the major nucleolar protein, fibrillarin, in vitro. 2008. Journal Molecular Biology, 376, 932-937.

5.      Obraztsova E.A., Kalinina N.O., Taliansky M.E., Gabrenaite-Verkhovskaya R., Mäkinen K. and Yaminsky I.V. 2008. Atomic force microscopy of potato virus A. Colloid Journal, 70, 199-201.

6.      Makarov V.V., Dobrov E.N., Taliansky M.E., Kalinina N.O. N-terminal portion of hordeivirus movement TGB1 protein consists of two domains with different content of disordered structure. "Flexible viruses: structural disorder in viral proteins" (Longhi S. and Uversky V.N., Eds.). 2012, 445-472.

7.      Makarov V., Rakitina D., Protopopova A., Yaminsky I., Arutiunian A., Love A.J., Taliansky M., Kalinina N. Plant oilin: Structural Characteristics and RNA-Binding Properties. PLoS ONE. 2013, 8(1): e53571. doi:10.1371/journal.pone.0053571

 

 

Makarov Valentin Vladimirovich

IMG_0019

 

Occupation in ATC: scientific researcher.

Other affiliations: Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology, scientific researcher.

Field of scientific interests: plant viruses, physicochemical methods of analysis of biopolymers, structure of virus and virus-like particles.

 

 

Selected publications:

1.      Makarov V., Rakitina D., Protopopova A., Yaminsky I., Arutiunian A., Love A.J., Taliansky M., Kalinina N. Plant Coilin: Structural Characteristics and RNA-Binding Properties. PloS ONE 2013, 8(1): e53571. doi:10.1371/journal.pone.0053571

2.      Makarov V.V., Dobrov E.N., Taliansky M.E., Kalinina N.O. N-terminal portion of hordeivirus movement TGB1 protein consists of two domains with different content of disordered structure. "Flexible viruses: structural disorder in viral proteins" (Longhi S. and Uversky V.N., Eds.). 2012, 445-472.

3.      Makarov V.V., Obraztsova E.A., Solovyev A.G., Morozov S.Y., Taliansky M.E., Yaminsky I.V., Kalinina N.O. The internal domain of hordeivirus movement protein TGB1 forms in vitro filamentous structures. Biochemistry (Mosc). 2010, 75, 752-758.

4.      Makarov V.V., Rybakova E.N., Efimov A.V., Dobrov E.N., Serebryakova M.V., Solovyev A.G., Yaminsky I.V., Taliansky M.E., Morozov S.Y., Kalinina N.O.. Domain organization of the N-terminal portion of hordeivirus movement protein TGBp1. 2009, Journal of General Virology, 90, 3022-3032.

 

Peter V. Gorelkin

 

Occupation in ATC: scientific researcher.

Other affiliations: Ltd. Medicine of the future, Director.

Field of scientific interests: scanning probe microscopy, biosensors.

 

 

Selected publications:

1.      Gorelkin P.V., Mukhin D.S., Majouga A.G., Romashkina R.B., Beloglazkina E.K., Yaminsky I.V., Zyk N.V. New self assembled coated cantilever for histidine protein immobilization // Mendeleev commun., 2010, Vol. 20, P. 329 331.

2.      Beloglazkina E.K., Majouga A.G., Zyk N.V., Rakhimov R.D., Yaminsky I.V., Gorelkin P.V., Kiselev G.A., Kutateladze A.G. Bis-(4-(2- pyridylmethyleneiminophenyl))disulfide A chelating ligand capable of self assembly on gold surface and its complexes with M(BF4)2 and M(ClO4)2; M Co, Cu and Ni. Experimental and theoretical study // Thin solid films, 2007, Vol.515, No.11, P.4649 4661.

3.      Yaminsky I.V, Gorelkin P.V., Kiselev G.A. Concurrence of Intermolecular Forces in Monolayers // Japanese Journal of Applied Physics, 2006, Vol. 45, No. 3B, P. 2316- 2318.

 

 

Olga V. Sinitsyna

 

 

Occupation in ATC: scientific researcher.

Other affiliations: INEOS RAS, MSU.

Field of scientific interests: scanning probe microscopy of macromolecular compounds, carbon materials and composites.

 

 

Selected publications:

9.    N.K. Davydova, O.V. Sinitsyna, I.V. Yaminsky, E.V. Kalinina, K.E. Zinoviev. Synthesis and Study of New Copolymers Capable of Forming Molecular Complexes with DNA. Macromolecular Symposia. Special Issue: Polymer Blends, 321-322 (2012) 8489.

10.              I.A. Ronova, O.V. Sinitsyna, S.S. Abramchuk, A.Yu. Nikolaeva, S. Chisca, I. Sava, M. Bruma. Study of porous structure of polyimide films resulting by using various methods. J. of Supercritical Fluids 70 (2012) 146155.

11.              O.V. Sinitsyna, G.B. Meshkov, I.V. Yaminsky. A novel tool for the local anodic oxidation of graphite. Proc. IMechE, Part N: J. Nanoengineering and Nanosystems, 224 (2010) 133-138.

12.              O.V. Sinitsyna, I.V. Yaminsky. Atomic resolution probe microscopy of the graphite surface. Russian Chemical Reviews 75 (2006) 23-30.

 

 

 

Makarova Svetlana Sergeevna

IMG_0022

 

Occupation in ATC: scientific researcher.

Other affiliations: Lomonosov Moscow State University, biological department, scientific researcher.

Field of scientific interests: plant viruses, molecular physiology of plants, plant proteins.

 

 

Selected publications:

1.    Makarova S.S., Minina E.A., Makarov V.V., Semenyuk P.I., Kopertekh L., Schiemann J., Serebryakova M.V., Erokhina T.N., Solovyev A.G., Morozov S.Y. Orthologues of a plant-specific At-4/1 gene in the genus Nicotiana and the structural properties of bacterially expressed 4/1 protein. Biochimie. 2011, 93, 1770-1778.

2.    Globa E.B., Demidova E.V., Tyrkin V.V., Makarova S.S., Nosov A.M. The comparative research of callusogenesis and obtaining suspension cell cultures of four species of a yew: Taxus canadensis, T.baccata, T.cuspidata, T.media. Biotechnology (Mosc), 2009, 3, 54-59.

 

 

 

Anna O. Dudnik

 

 

 

Occupation in ATC: scientific researcher.

Other affiliations: student of the Physics Department of the MSU

Field of scientific interests: scanning probe and transmission electron microscopy of nanoparticles, viruses.

 

 

 

Michael Taliansky

Affiliation: The James Hutton Institute

Collaborator

Field of scientific interests: molecular virology, plant biotechnology and molecular biology. Development of original approaches and promising methods of nanoparticles production using plant extracts, including plant virus virions and virus-like particles. Synthesis of artificial virus-like particles, which can be used as biomatrices.

 

 

 

 

Participants Results Publications ATC